SCHEMBL17949690

SCHEMBL17949690

c1ccc2c(c1)CNc1ccccc1-c1nn[nH]c1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 2/20 0.40
▸ CA9 Q16790 2/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ JAK2 O60674 1/20 0.38
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ PLK4 O00444 1/20 0.36
▸ DAPK3 O43293 1/20 0.36
▸ PIM1 P11309 1/20 0.36
▸ PDGFRA P16234 1/20 0.36
▸ LTK P29376 1/20 0.36
▸ MAP2K2 P36507 1/20 0.36
▸ FLT3 P36888 1/20 0.36
▸ MAPK8 P45983 1/20 0.36
▸ MAPK9 P45984 1/20 0.36
▸ CSNK1A1 P48729 1/20 0.36
▸ TDO2 P48775 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30340726 1.00 CA12 (0.40) CA12CA9ALOX15HSD17B10JAK2
SCHEMBL20503690 0.94 CA12 (0.40) CA12CA9ALOX15HSD17B10JAK2
SCHEMBL30096606 0.94 CA12 (0.40) CA12CA9ALOX15HSD17B10JAK2
SCHEMBL23044043 0.78 KDM4E (0.41) PLK4DAPK3PIM1PDGFRALTK
SCHEMBL21340386 0.76 ACVR1 (0.39) GAAPDGFRALTKCDK8CDK5
SCHEMBL20854469 0.75 METAP2 (0.53) CA12CA9ALOX15HSD17B10JAK2
Dihydrophenanthridine SCHEMBL29791568 0.73 CA12 (0.56) CA12CA9ALOX15HSD17B10JAK2
Dihydrophenanthridine SCHEMBL2087461 0.73 CA12 (0.56) CA12CA9ALOX15HSD17B10JAK2
SCHEMBL24976109 0.73 ALDH1A1 (0.37) HSD17B10GAAPLK4DAPK3PIM1
SCHEMBL727511 0.73 ALDH1A1 (0.37) HSD17B10GAAPLK4DAPK3PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096366-A1 CONJUGATES FOR DELIVERY ACROSS THE BLOOD BRAIN BARRIER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2025-05-08 — — WO claimed
US-20260144856-A1 VACCINE AGAINST KLEBSIELLA PNEUMONIAE IDORSIA PHARMACEUTICALS LTD (CH) 2026-05-28 — — US disclosed
US-20250228954-A1 Designing Antisense Oligonucleotide Delivery Peptides by Interpretable Machine Learning SAREPTA THERAPEUTICS INC (US) 2025-07-17 — — US disclosed
US-20250224411-A1 MOLECULAR HOPPER OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-07-10 — — US disclosed
US-20250171776-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY SAREPTA THERAPEUTICS, INC. (US) 2025-05-29 — — US disclosed
US-20250161469-A1 TRIMERIC PEPTIDES FOR ANTISENSE DELIVERY SAREPTA THERAPEUTICS, INC. 2025-05-22 — — US disclosed
WO-2025096366-A1 CONJUGATES FOR DELIVERY ACROSS THE BLOOD BRAIN BARRIER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2025-05-08 — — WO disclosed
US-12247990-B2 Molecular hopper OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-03-11 — — US disclosed
WO-2025030099-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY SAREPTA THERAPEUTICS, INC. (US) 2025-02-06 — — WO disclosed
US-20250011777-A1 DELIVERY OF ANITSENSE OLIGOMERS BY MIRROR IMAGE PEPTIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-01-09 — — US disclosed
EP-3829597-A1 TRIMERIC PEPTIDES FOR ANTISENSE DELIVERY Sarepta Therapeutics, Inc. (US) 2021-06-09 — — EP disclosed
WO-2020252015-A1 IMMUNOMODULATOR ANTIBODY DRUG CONJUGATES AND USES THEREOF SUTRO BIOPHARMA, INC. (US) 2020-12-17 — — WO disclosed
US-20200353076-A1 ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES SUTRO BIOPHARMA, INC. 2020-11-12 — — US disclosed
WO-2020028254-A1 TRIMERIC PEPTIDES FOR ANTISENSE DELIVERY SAREPTA THERAPEUTICS, INC. (US) 2020-02-06 — — WO disclosed
US-10435479-B2 Chemically-locked bispecific antibodies SORRENTO THERAPEUTICS, INC. (US) 2019-10-08 — — US disclosed
US-20190248923-A1 CHEMICALLY-LOCKED BISPECIFIC ANTIBODIES SORRENTO THERAPEUTICS, INC. (US) 2019-08-15 — — US disclosed
US-10301395-B2 Chemically-locked bispecific antibodies SORRENTO THERAPEUTICS, INC. (US) 2019-05-28 — — US disclosed
EP-3377112-A1 CHEMICALLY-LOCKED BISPECIFIC ANTIBODIES Sorrento Therapeutics, Inc. (US) 2018-09-26 — — EP disclosed
US-20170137539-A1 CHEMICALLY-LOCKED BISPECIFIC ANTIBODIES SORRENTO THERAPEUTICS, INC. 2017-05-18 — — US disclosed
US-20160215020-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS APELLIS PHARMACEUTICALS, INC. (US) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011777-A1 DELIVERY OF ANITSENSE OLIGOMERS BY MIRROR IMAGE PEPTIDES MYOF, IAPP, MTPN CA12 2588/4885CA9 4084/4885ALOX15 3698/4885
US-20200353076-A1 ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES FOLR2, FOLR1, FCGRT CA12 512/4885CA9 3822/4885ALOX15 2600/4885
US-20190248923-A1 CHEMICALLY-LOCKED BISPECIFIC ANTIBODIES CD274, CD22, CXCR3 CA12 763/4885CA9 1380/4885ALOX15 3371/4885
US-20160215020-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS C3AR1, C9, C1QBP CA12 2632/4885CA9 3161/4885ALOX15 1784/4885
US-10301395-B2 Chemically-locked bispecific antibodies CD274, CD47, CD22 CA12 922/4885CA9 1439/4885ALOX15 3475/4885
US-20260144856-A1 VACCINE AGAINST KLEBSIELLA PNEUMONIAE PKLR, RPS17, OSTC CA12 398/4885CA9 1475/4885ALOX15 3776/4885
US-20250171776-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY MYOF, TNNC1, MTPN CA12 3111/4885CA9 3474/4885ALOX15 2687/4885
US-20170137539-A1 CHEMICALLY-LOCKED BISPECIFIC ANTIBODIES CD274, CD47, CD22 CA12 922/4885CA9 1439/4885ALOX15 3475/4885
US-20250161469-A1 TRIMERIC PEPTIDES FOR ANTISENSE DELIVERY MTPN, MYOF, IAPP CA12 2137/4885CA9 3240/4885ALOX15 4120/4885
US-10435479-B2 Chemically-locked bispecific antibodies FCGR3B, FCGR2A, FCGR1A CA12 1200/4885CA9 2730/4885ALOX15 3039/4885
US-20250228954-A1 Designing Antisense Oligonucleotide Delivery Peptides by Interpretable Machine Learning MTPN, TNNC1, MYOF CA12 2624/4885CA9 3486/4885ALOX15 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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