Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 19/20 | 0.49 |
| ▸ | FPR2 | P25090 | 19/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24337033 | 0.87 | FPR2 (0.65) | FPR1FPR2 | |
| SCHEMBL21319266 | 0.87 | FPR2 (0.65) | FPR1FPR2 | |
| SCHEMBL30832912 | 0.87 | FPR2 (0.65) | FPR1FPR2 | |
| SCHEMBL24093591 | 0.84 | FPR2 (0.48) | FPR1FPR2 | |
| SCHEMBL25712974 | 0.81 | FPR2 (0.49) | FPR1FPR2 | |
| SCHEMBL24093677 | 0.80 | FPR2 (0.46) | FPR1FPR2 | |
| SCHEMBL21341184 | 0.80 | FPR1 (0.41) | FPR1FPR2HDAC1HDAC8HDAC6 | |
| SCHEMBL30832910 | 0.80 | FPR1 (0.41) | FPR1FPR2HDAC1HDAC8HDAC6 | |
| SCHEMBL24093594 | 0.79 | FPR1 (0.79) | FPR1FPR2 | |
| SCHEMBL24093581 | 0.77 | FPR1 (0.52) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981767-A1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2022-04-13 | — | — | EP | disclosed |
| EP-3762380-B1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2019173182-A1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-12 | — | — | WO | disclosed |