SCHEMBL24093591

SCHEMBL24093591

CNC1CC(C)N(c2ccc(-c3ccccc3P(C)C)c(F)c2F)C1=O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 20/20 0.48
FPR1 P21462 19/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24093677 0.89 FPR2 (0.46) FPR2FPR1
SCHEMBL21340862 0.84 FPR1 (0.49) FPR2FPR1
SCHEMBL24337058 0.83 FPR2 (0.65) FPR2FPR1
SCHEMBL24093672 0.79 FPR2 (0.49) FPR2FPR1
SCHEMBL24093594 0.78 FPR1 (0.79) FPR2FPR1
SCHEMBL24093620 0.78 FPR2 (0.38) FPR2FPR1
SCHEMBL24093585 0.74 FPR1 (0.47) FPR2FPR1
SCHEMBL22320943 0.73 FPR2 (0.70) FPR2FPR1
SCHEMBL24093543 0.72 FPR2 (0.50) FPR2FPR1
SCHEMBL24337059 0.72 FPR2 (0.49) FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762380-B1 PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-12-15 EP disclosed