Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | FPR1 | P21462 | 9/20 | 0.52 |
| ▸ | FPR2 | P25090 | 7/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21341976 | 1.00 | KDM1A (0.53) | KDM1AFPR1FPR2MAOBMAOA | |
| SCHEMBL21341962 | 1.00 | KDM1A (0.53) | KDM1AFPR1FPR2MAOBMAOA | |
| SCHEMBL19988652 | 0.91 | FPR1 (0.62) | KDM1AFPR1FPR2MAOBMAOA | |
| SCHEMBL19988379 | 0.91 | FPR1 (0.62) | KDM1AFPR1FPR2MAOBMAOA | |
| SCHEMBL21331936 | 0.87 | FPR1 (0.56) | FPR1FPR2MAP2K1TSHR | |
| SCHEMBL21342009 | 0.83 | FPR1 (0.56) | KDM1AFPR1FPR2 | |
| SCHEMBL18609449 | 0.82 | FPR1 (0.60) | KDM1AFPR1FPR2 | |
| SCHEMBL18609243 | 0.82 | FPR1 (0.60) | KDM1AFPR1FPR2 | |
| SCHEMBL18117785 | 0.82 | FPR1 (0.60) | KDM1AFPR1FPR2 | |
| SCHEMBL29434176 | 0.82 | FPR1 (0.60) | KDM1AFPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |