Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 16/20 | 0.60 |
| ▸ | FPR2 | P25090 | 15/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18578795 | 1.00 | FPR1 (0.60) | FPR1FPR2KDM1A | |
| SCHEMBL18106404 | 1.00 | FPR1 (0.60) | FPR1FPR2KDM1A | |
| SCHEMBL18609449 | 1.00 | FPR1 (0.60) | FPR1FPR2KDM1A | |
| SCHEMBL29434176 | 1.00 | FPR1 (0.60) | FPR1FPR2KDM1A | |
| SCHEMBL18106402 | 1.00 | FPR1 (0.60) | FPR1FPR2KDM1A | |
| SCHEMBL18117785 | 1.00 | FPR1 (0.60) | FPR1FPR2KDM1A | |
| SCHEMBL18106592 | 0.84 | FPR2 (0.66) | FPR1FPR2 | |
| SCHEMBL18264316 | 0.84 | FPR2 (0.66) | FPR1FPR2 | |
| SCHEMBL21341976 | 0.82 | KDM1A (0.53) | FPR1FPR2KDM1A | |
| SCHEMBL21341982 | 0.82 | KDM1A (0.53) | FPR1FPR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464891-B2 | Urea derivative or pharmacologically acceptable salt thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2019-11-05 | — | — | US | disclosed |
| US-10252992-B2 | Urea derivative or pharmacologically acceptable salt thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2019-04-09 | — | — | US | disclosed |
| US-10029983-B2 | Urea derivative or pharmacologically acceptable salt thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20180044290-A1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | KYORIN SEIYAKU KK (JP) | 2018-02-15 | — | — | US | disclosed |
| US-9822069-B2 | Urea derivative or pharmacologically acceptable salt thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2017-11-21 | — | — | US | disclosed |
| US-20170066718-A1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464891-B2 | Urea derivative or pharmacologically acceptable salt thereof | FPR1, FPR2, FPR3 | FPR1 1/4885FPR2 2/4885KDM1A 4486/4885 |
| US-10029983-B2 | Urea derivative or pharmacologically acceptable salt thereof | FPR1, FPR2, FPR3 | FPR1 1/4885FPR2 2/4885KDM1A 4486/4885 |
| US-20170066718-A1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | FPR1, FPR2, FPR3 | FPR1 1/4885FPR2 2/4885KDM1A 4486/4885 |
| US-20180044290-A1 | UREA DERIVATIVE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF | FPR1, FPR2, FPR3 | FPR1 1/4885FPR2 2/4885KDM1A 4486/4885 |
| US-10252992-B2 | Urea derivative or pharmacologically acceptable salt thereof | FPR1, FPR2, FPR3 | FPR1 1/4885FPR2 2/4885KDM1A 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.