Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 14/20 | 0.53 |
| ▸ | FPR2 | P25090 | 11/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581283 | 0.82 | FPR2 (0.55) | FPR1FPR2KDM1AKDM1B | |
| SCHEMBL18117787 | 0.81 | MTNR1A (0.64) | FPR1FPR2MTNR1A | |
| SCHEMBL19559399 | 0.81 | MTNR1A (0.64) | FPR1FPR2MTNR1A | |
| SCHEMBL21331949 | 0.80 | FPR1 (0.61) | FPR1FPR2 | |
| SCHEMBL19985868 | 0.79 | FPR1 (0.57) | FPR1FPR2MTNR1A | |
| SCHEMBL19972416 | 0.79 | FPR1 (0.57) | FPR1FPR2MTNR1A | |
| SCHEMBL19972418 | 0.79 | FPR1 (0.57) | FPR1FPR2MTNR1A | |
| SCHEMBL19972238 | 0.79 | FPR1 (0.57) | FPR1FPR2MTNR1A | |
| SCHEMBL19972357 | 0.78 | FPR1 (0.59) | FPR1FPR2MTNR1A | |
| SCHEMBL19972289 | 0.77 | FPR1 (0.72) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |