Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.52 |
| ▸ | PROKR1 | Q8TCW9 | 8/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342442 | 0.88 | PROKR1 (0.54) | PRKDCPROKR1MYCALDH1A1LMNA | |
| SCHEMBL21341953 | 0.87 | PRKDC (0.52) | PRKDCPROKR1MYCALDH1A1LMNA | |
| SCHEMBL21341987 | 0.84 | PRKDC (0.52) | PRKDCPROKR1ALDH1A1LMNAHPGD | |
| SCHEMBL21342321 | 0.82 | PRKDC (0.56) | PRKDCPROKR1MYCALDH1A1LMNA | |
| SCHEMBL21341961 | 0.81 | FPR1 (0.48) | PRKDCPROKR1MYCALDH1A1LMNA | |
| SCHEMBL21342319 | 0.78 | CHRM4 (0.51) | PRKDCPROKR1ALDH1A1LMNAHPGD | |
| SCHEMBL21341991 | 0.78 | PRKDC (0.51) | PRKDCPROKR1MYCALDH1A1LMNA | |
| SCHEMBL21342048 | 0.76 | ALDH1A1 (0.52) | PRKDCPROKR1ALDH1A1LMNAHPGD | |
| SCHEMBL17602186 | 0.76 | ALDH1A1 (0.61) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21341955 | 0.76 | AVPR1A (0.54) | PRKDCPROKR1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |