Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21341991 | 0.87 | PRKDC (0.51) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21341987 | 0.86 | PRKDC (0.52) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21342321 | 0.84 | PRKDC (0.56) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21341961 | 0.84 | FPR1 (0.48) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21342402 | 0.81 | PRKDC (0.43) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL17602186 | 0.80 | ALDH1A1 (0.61) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21342443 | 0.80 | ROCK2 (0.45) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21342442 | 0.78 | PROKR1 (0.54) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21342320 | 0.78 | PRKDC (0.52) | PRKDCALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL21342048 | 0.78 | ALDH1A1 (0.52) | PRKDCALDH1A1LMNAHPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |