Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342896 | 0.89 | IDH1 (0.36) | IDH1KDM4EGPR119 | |
| SCHEMBL21342933 | 0.85 | ALDH1A1 (0.33) | MEN1KMT2AKDM4EBLMNPSR1 | |
| SCHEMBL21342164 | 0.83 | MEN1 (0.34) | MEN1KMT2AKDM4EBLMNPSR1 | |
| SCHEMBL21342501 | 0.82 | IDH1 (0.33) | IDH1KDM4EGPR119 | |
| SCHEMBL21342893 | 0.80 | IDH1 (0.31) | IDH1 | |
| SCHEMBL21342500 | 0.80 | KMT2A (0.41) | MEN1KMT2AKDM4ENPSR1CYP3A4 | |
| SCHEMBL21342166 | 0.80 | IDH1 (0.31) | IDH1GPR119 | |
| SCHEMBL21342936 | 0.80 | ALDH1A1 (0.34) | MEN1KMT2AIDH1KDM4EGPR119 | |
| SCHEMBL21342502 | 0.77 | POLB (0.32) | MEN1KMT2AKDM4E | |
| SCHEMBL21342486 | 0.76 | KMT2A (0.40) | MEN1KMT2AKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | PENN STATE RES FOUND (US) | 2021-04-01 | — | — | US | disclosed |
| WO-2019173607-A1 | DYES FOR ANALYSIS OF SOLUBLE PROTEIN AGGREGATES OR MISFOLDED PROTEIN OLIGOMERS | THE PENN STATE RESEARCH FOUNDATION (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | HSPBP1, HTT, HSPA5 | MEN1 4014/4885KMT2A 4328/4885IDH1 1665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.