Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342936 | 0.91 | ALDH1A1 (0.34) | IDH1GPR119KDM4E | |
| SCHEMBL21342501 | 0.91 | IDH1 (0.33) | IDH1GPR119KDM4E | |
| SCHEMBL21342166 | 0.89 | IDH1 (0.31) | IDH1GPR119 | |
| SCHEMBL21342891 | 0.89 | MEN1 (0.33) | IDH1GPR119KDM4E | |
| SCHEMBL21342500 | 0.87 | KMT2A (0.41) | KDM4E | |
| SCHEMBL21342893 | 0.87 | IDH1 (0.31) | IDH1 | |
| SCHEMBL21342486 | 0.86 | KMT2A (0.40) | KDM4E | |
| SCHEMBL21342502 | 0.83 | POLB (0.32) | KDM4E | |
| SCHEMBL21342160 | 0.83 | POLB (0.32) | KDM4E | |
| SCHEMBL23172953 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | PENN STATE RES FOUND (US) | 2021-04-01 | — | — | US | disclosed |
| WO-2019173607-A1 | DYES FOR ANALYSIS OF SOLUBLE PROTEIN AGGREGATES OR MISFOLDED PROTEIN OLIGOMERS | THE PENN STATE RESEARCH FOUNDATION (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094922-A1 | Dyes for Analysis of Soluble Protein Aggregates or Misfolded Protein Oligomers | HSPBP1, HTT, HSPA5 | IDH1 1665/4885GPR119 4731/4885BCHE 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.