Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.35 |
| ▸ | FASN | P49327 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992243 | 1.00 | CNR2 (0.37) | CNR2EPHX2FASNPIK3CDPIK3CA | |
| SCHEMBL21343721 | 0.94 | EPHX2 (0.38) | CNR2EPHX2FASNPIK3CANAMPT | |
| SCHEMBL21344743 | 0.91 | MGLL (0.33) | MGLL | |
| SCHEMBL22992014 | 0.90 | BRD4 (0.37) | PIK3CABRD4GRM5MGLLALDH1A1 | |
| SCHEMBL22992046 | 0.89 | EPHX2 (0.36) | CNR2EPHX2NAMPTMGLLALDH1A1 | |
| SCHEMBL21332010 | 0.88 | ALDH1A1 (0.34) | BRD4MGLLALDH1A1POLBKMT2A | |
| SCHEMBL21344275 | 0.86 | ALDH1A1 (0.43) | ALDH1A1POLBKMT2A | |
| SCHEMBL21344280 | 0.85 | NAMPT (0.33) | PIK3CDPIK3CANAMPTALDH1A1 | |
| SCHEMBL21343901 | 0.85 | NAMPT (0.33) | PIK3CDPIK3CANAMPTALDH1A1 | |
| SCHEMBL22992242 | 0.85 | NAMPT (0.33) | PIK3CDPIK3CANAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | CNR2 1256/4885EPHX2 63/4885FASN 741/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | CNR2 1256/4885EPHX2 63/4885FASN 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.