SCHEMBL22992014

SCHEMBL22992014

CC#Cc1cc(C)c(C2C(=O)CC3(CCN(C(=O)C4CCC4)CC3)CC2=O)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.37
CNR1 P21554 1/20 0.35
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
ADAM17 P78536 1/20 0.34
TSHR P16473 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
GRM5 P41594 1/20 0.33
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HRH3 Q9Y5N1 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MGLL Q99685 2/20 0.32
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21332010 0.96 ALDH1A1 (0.34) BRD4CNR1MEN1KMT2AADAM17
SCHEMBL22992046 0.91 EPHX2 (0.36) MEN1KMT2AL3MBTL1HRH3ALDH1A1
SCHEMBL29341749 0.90 CNR1 (0.33) BRD4CNR1MEN1KMT2AADAM17
SCHEMBL21343718 0.90 CNR2 (0.37) BRD4KMT2APIK3CAGRM5ALDH1A1
SCHEMBL22992243 0.90 CNR2 (0.37) BRD4KMT2APIK3CAGRM5ALDH1A1
SCHEMBL21344743 0.89 MGLL (0.33) MGLL
SCHEMBL22992234 0.88 GAA (0.38) MEN1KMT2ATSHRMAPTALDH1A1
SCHEMBL22942018 0.88 RORC (0.32) BRD4CNR1TSHR
SCHEMBL21343721 0.87 EPHX2 (0.38) KMT2APIK3CAGRM5
SCHEMBL21344275 0.86 ALDH1A1 (0.43) MEN1KMT2ATSHRL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043599-B2 Herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2024-07-23 US disclosed
US-12043599-B2 Herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2024-07-23 US disclosed
EP-3762378-B1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2022-05-18 EP disclosed
US-20210047274-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047274-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 BRD4 2582/4885CNR1 965/4885MEN1 3738/4885
US-12043599-B2 Herbicidal compounds DDT, CBR3, GLRX3 BRD4 2582/4885CNR1 965/4885MEN1 3738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.