Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992263 | 0.88 | LMNA (0.30) | LMNAMAPTALOX12HTTSMN1; SMN2 | |
| SCHEMBL21343913 | 0.80 | LMNA (0.31) | LMNAMAPTALOX12HTTSMN1; SMN2 | |
| SCHEMBL21361221 | 0.79 | USP2 (0.40) | ALOX12SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL21344707 | 0.78 | — | — | |
| SCHEMBL22992230 | 0.76 | LMNA (0.31) | LMNAMAPTALOX12HTTSMN1; SMN2 | |
| SCHEMBL21344686 | 0.76 | LMNA (0.31) | LMNAMAPTALOX12HTTSMN1; SMN2 | |
| SCHEMBL21344678 | 0.76 | LMNA (0.31) | LMNAMAPTALOX12HTTSMN1; SMN2 | |
| SCHEMBL21343740 | 0.76 | MEN1 (0.36) | SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL21344745 | 0.76 | FFAR4 (0.32) | — | |
| SCHEMBL21343876 | 0.76 | MGLL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |