⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344260 | 0.89 | — | — | |
| SCHEMBL21344248 | 0.89 | HIF1A (0.32) | — | |
| SCHEMBL22992125 | 0.87 | CYP2D6 (0.33) | — | |
| SCHEMBL22992095 | 0.87 | PIK3CA (0.34) | — | |
| SCHEMBL21332010 | 0.87 | ALDH1A1 (0.34) | — | |
| SCHEMBL21343875 | 0.86 | — | — | |
| SCHEMBL21344282 | 0.86 | HIF1A (0.31) | — | |
| SCHEMBL22992166 | 0.86 | EPHX2 (0.36) | — | |
| SCHEMBL21343728 | 0.85 | CYP3A4 (0.31) | — | |
| SCHEMBL22992196 | 0.84 | RAB9A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |