Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | MMP14 | P50281 | 3/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992138 | 0.87 | CHRM2 (0.40) | ALDH1A1HPGDHSD17B10NSD2USP2 | |
| SCHEMBL21344268 | 0.86 | KDM4E (0.37) | KCNH2HCRTR1HCRTR2ALDH1A1NSD2 | |
| SCHEMBL29342691 | 0.86 | DPP4 (0.39) | DPP4KCNH2HCRTR1HCRTR2 | |
| SCHEMBL22992040 | 0.86 | CYP3A4 (0.47) | ALDH1A1HPGDHSD17B10USP2CYP3A4 | |
| SCHEMBL22908443 | 0.86 | KCNH2 (0.34) | DPP4KCNH2HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL21344274 | 0.85 | ACACA (0.32) | ACACA | |
| SCHEMBL21343720 | 0.85 | NPY2R (0.37) | KCNH2HCRTR1HCRTR2ALDH1A1HPGD | |
| SCHEMBL22992155 | 0.85 | CYP3A4 (0.44) | ALDH1A1HPGDHSD17B10USP2CYP3A4 | |
| SCHEMBL22992053 | 0.85 | CHRNA4 (0.36) | ALDH1A1HPGDHSD17B10USP2CYP3A4 | |
| SCHEMBL22992134 | 0.85 | MGLL (0.36) | USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | DPP4 417/4885KCNH2 300/4885HCRTR1 102/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | DPP4 417/4885KCNH2 300/4885HCRTR1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.