Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344670 | 0.91 | CHRM2 (0.42) | CYP3A4CYP2C9USP2CYP2C19ALDH1A1 | |
| SCHEMBL21344669 | 0.90 | CHRM2 (0.45) | ALDH1A1MAPK1 | |
| SCHEMBL22992057 | 0.89 | ACACA (0.38) | CYP3A4CYP2D6CYP2C9HSD17B10TSHR | |
| SCHEMBL21344672 | 0.89 | VNN1 (0.36) | CYP3A4 | |
| SCHEMBL22992179 | 0.89 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9HSD17B10TSHR | |
| SCHEMBL21344679 | 0.89 | NAMPT (0.42) | CYP2D6CYP2C9HSD17B10TSHRUSP2 | |
| SCHEMBL22992214 | 0.88 | CCR8 (0.42) | CYP3A4CYP2D6CYP2C9HSD17B10TSHR | |
| SCHEMBL21343895 | 0.88 | CYP2C9 (0.37) | CYP3A4CYP2D6CYP2C9HSD17B10TSHR | |
| SCHEMBL21344846 | 0.87 | CYP3A4 (0.38) | CYP3A4CYP2D6CYP2C9TSHRUSP2 | |
| SCHEMBL22992138 | 0.86 | CHRM2 (0.40) | CYP3A4CYP2D6CYP2C9HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | CYP3A4 245/4885CYP2D6 120/4885CYP2C9 73/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | CYP3A4 245/4885CYP2D6 120/4885CYP2C9 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.