Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 10/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 4/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344694 | 0.92 | BACE1 (0.33) | BACE1BACE2 | |
| SCHEMBL22992248 | 0.92 | IRAK4 (0.35) | GPR6BACE1BACE2 | |
| SCHEMBL21344698 | 0.91 | BACE1 (0.36) | BACE1BACE2 | |
| SCHEMBL21343897 | 0.90 | CYP1A2 (0.35) | GPR6DRD3BACE1BACE2 | |
| SCHEMBL22992072 | 0.90 | TRPV1 (0.36) | BACE1BACE2 | |
| SCHEMBL22942059 | 0.88 | RAB9A (0.35) | NAMPT | |
| SCHEMBL21344693 | 0.85 | ALDH1A1 (0.32) | — | |
| SCHEMBL21343728 | 0.84 | CYP3A4 (0.31) | NAMPT | |
| SCHEMBL21343726 | 0.84 | NAMPT (0.33) | NAMPT | |
| SCHEMBL21344691 | 0.84 | CYP1A2 (0.35) | GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |