Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 10/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 7/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344680 | 0.92 | NAMPT (0.35) | BACE1BACE2GPR6 | |
| SCHEMBL21344694 | 0.91 | BACE1 (0.33) | BACE1BACE2APP | |
| SCHEMBL22992072 | 0.90 | TRPV1 (0.36) | BACE1BACE2APP | |
| SCHEMBL21344698 | 0.89 | BACE1 (0.36) | BACE1BACE2 | |
| SCHEMBL21343897 | 0.89 | CYP1A2 (0.35) | BACE1BACE2GPR6 | |
| SCHEMBL21344693 | 0.89 | ALDH1A1 (0.32) | — | |
| SCHEMBL22942059 | 0.87 | RAB9A (0.35) | KCNH2GRM4 | |
| SCHEMBL21344692 | 0.85 | CLK1 (0.33) | IRAK4GRM4 | |
| SCHEMBL21344695 | 0.84 | TRPV1 (0.36) | BACE1GPR6GRM5 | |
| SCHEMBL21343728 | 0.83 | CYP3A4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | IRAK4 4128/4885BACE1 2863/4885BACE2 1789/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | IRAK4 4128/4885BACE1 2863/4885BACE2 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.