Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344781 | 0.91 | LMNA (0.33) | LMNACYP3A4CYP2D6HIF1ATSHR | |
| SCHEMBL22886729 | 0.88 | — | — | |
| SCHEMBL22855326 | 0.86 | SLC6A1 (0.32) | CYP3A4CYP2D6HIF1APTPN1 | |
| SCHEMBL22855701 | 0.85 | LMNA (0.45) | LMNACYP3A4CYP2D6TSHRCA12 | |
| SCHEMBL22830211 | 0.85 | LMNA (0.36) | LMNACYP3A4CYP2D6TSHRCA12 | |
| SCHEMBL21345093 | 0.83 | — | — | |
| SCHEMBL21344947 | 0.81 | CA2 (0.41) | LMNACYP2D6TSHRCA12CA9 | |
| SCHEMBL22855465 | 0.81 | CA2 (0.41) | LMNACYP2D6TSHRCA12CA9 | |
| SCHEMBL21344783 | 0.79 | KMT2A (0.40) | CYP3A4CYP2D6HIF1ACYP2C19KMT2A | |
| SCHEMBL22855491 | 0.79 | KMT2A (0.40) | CYP3A4CYP2D6HIF1ACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019172286-A1 | THERAPEUTIC AGENT FOR GLYCOGEN STORAGE DISEASE TYPE IA | 第一三共株式会社 | 2019-09-12 | — | — | WO | disclosed |