Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 4/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eniluracil SCHEMBL37817 | 0.78 | DPYD (1.00) | DPYDGAAATAD2ALDH1A1LMNA | |
| SCHEMBL4373860 | 0.76 | DPYD (0.41) | DPYDMMP2GAAATAD2ALDH1A1 | |
| SCHEMBL8509899 | 0.72 | DPYD (0.38) | DPYDMMP2ATAD2 | |
| SCHEMBL23622043 | 0.71 | DPYD (0.64) | DPYDGAAALDH1A1MAPT | |
| Eniluracil SCHEMBL5392934 | 0.67 | DPYD (0.73) | DPYDMMP2GAAATAD2ALDH1A1 | |
| SCHEMBL65835 | 0.67 | — | — | |
| SCHEMBL1056570 | 0.67 | — | — | |
| SCHEMBL21345580 | 0.67 | GAA (0.39) | DPYDMMP2GAAATAD2ALDH1A1 | |
| SCHEMBL22571173 | 0.62 | ATAD2 (0.39) | DPYDMMP2GAAATAD2ALDH1A1 | |
| SCHEMBL4204491 | 0.62 | KDM3B (0.55) | DPYDMMP2GAAATAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173602-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2019-09-12 | — | — | WO | disclosed |