Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 2/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485393 | 0.82 | DPYD (0.53) | DPYDATAD2 | |
| SCHEMBL4373860 | 0.80 | DPYD (0.41) | DPYDATAD2MMP2 | |
| SCHEMBL8508879 | 0.76 | KMT2A (0.41) | DPYD | |
| SCHEMBL21345256 | 0.72 | DPYD (0.64) | DPYDATAD2MMP2 | |
| SCHEMBL1890981 | 0.69 | DPYD (0.50) | DPYDATAD2 | |
| SCHEMBL1050748 | 0.67 | DPYD (0.47) | DPYDATAD2 | |
| SCHEMBL65835 | 0.65 | — | — | |
| SCHEMBL22571173 | 0.64 | ATAD2 (0.39) | DPYDATAD2MMP2 | |
| SCHEMBL8507938 | 0.64 | TLR8 (0.34) | — | |
| SCHEMBL3485208 | 0.64 | TLR8 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923596-A2 | LIPOPHILIC OLIGONUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004575-A2 | LIPOPHILIC OLIGONUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1998-02-05 | — | — | WO | disclosed |