Eniluracil

Eniluracil

SCHEMBL37817

C#Cc1c[nH]c(=O)[nH]c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

DPYD

The experimentally established mechanism targets of Eniluracil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPYD known ✓ Q12882 5/20 1.00
MAPT P10636 3/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 2/20 0.46
LMNA P02545 2/20 0.46
ATAD2 Q6PL18 1/20 0.46
CYP19A1 P11511 1/20 0.46
TSHR P16473 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
HTT P42858 1/20 0.46
HBB P68871 1/20 0.46
PMP22 Q01453 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4C Q9H3R0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eniluracil SCHEMBL5392934 0.86 DPYD (0.73) DPYDMAPTALDH1A1GAALMNA
SCHEMBL21345256 0.78 DPYD (0.64) DPYDMAPTALDH1A1GAALMNA
SCHEMBL189451 0.77 DPYD (1.00) DPYDMAPTALDH1A1GAALMNA
SCHEMBL14177211 0.74 DPYD (0.59) DPYDMAPTALDH1A1GAALMNA
SCHEMBL13296 0.74 DPYD (0.59) DPYDMAPTALDH1A1GAALMNA
SCHEMBL1051435 0.74 DPYD (0.59) DPYDMAPTALDH1A1GAALMNA
SCHEMBL28592458 0.72 DPYD (0.57) DPYDMAPTALDH1A1GAALMNA
SCHEMBL31045516 0.72 DPYD (0.54) DPYDMAPTALDH1A1GAALMNA
SCHEMBL21295318 0.72 DPYD (0.54) DPYDMAPTALDH1A1GAALMNA
SCHEMBL3485393 0.70 DPYD (0.53) DPYDMAPTALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 25880 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
EP-4743490-A1 HUMANIZED ANTI-CD7 ANTIBODY Christian-Albrechts-Universität zu Kiel (DE) 2026-05-20 EP claimed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 WO claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
EP-4729063-A2 TREATMENT OF CANCER USING COENZYME Q10 COMBINATION THERAPIES BPGbio, Inc. (US) 2026-04-22 EP claimed
EP-4698185-A1 METHODS AND SYSTEMS FOR IMPROVING ANTI-CANCER THERAPIES Osasuna Therapeutics SA (CH) 2026-02-25 EP claimed
US-5643913-A SIDE EFFECTS REDUCTION FOR VIRICIDES AND AIDS TREATMENT GLAXO WELLCOME INC. (US) 1997-07-01 US claimed
WO-1996040165-A1 METHODS OF REDUCING TOXICITY OF CHEMOTHERAPEUTIC AND ANTIVIRAL AGENTS WITH ACYLATED PYRIMIDINE NUCLEOSIDES PRO-NEURON, INC. (US) 1996-12-19 WO claimed
EP-0726904-A1 5-FLUOROURACIL DERIVATIVES THE WELLCOME FOUNDATION LIMITED (GB) 1996-08-21 EP claimed
EP-0711555-A2 Enzyme inactivators THE WELLCOME FOUNDATION LIMITED (GB) 1996-05-15 EP claimed
WO-1995028489-A1 DIHYDROPYRIMIDINE DEHYDROGENASE COMPOSITIONS AND METHODS OF USE THE UAB RESEARCH FOUNDATION (US) 1995-10-26 WO claimed
WO-1995012606-A1 5-FLUOROURACIL DERIVATIVES THE WELLCOME FOUNDATION LIMITED (GB) 1995-05-11 WO claimed
EP-0550580-A1 URACIL REDUCTASE INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1993-07-14 EP claimed
EP-0539442-A1 ENZYME INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1993-05-05 EP claimed
WO-1992004901-A1 URACIL REDUCTASE INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1992-04-02 WO claimed
WO-1992001452-A1 ENZYME INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1992-02-06 WO claimed