SCHEMBL1760348

SCHEMBL1760348

CC1(C)c2cc(Br)ccc2-c2cc3[nH]c4ccccc4c3cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
PGR P06401 1/20 0.42
KIF11 P52732 6/20 0.41
CCNB2 O95067 2/20 0.39
CDK1 P06493 2/20 0.39
CCNB1 P14635 2/20 0.39
CDK5 Q00535 2/20 0.39
CDK5R1 Q15078 2/20 0.39
CCNB3 Q8WWL7 2/20 0.39
CCNT1 O60563 1/20 0.39
CCNE2 O96020 1/20 0.39
CDK4 P11802 1/20 0.39
EIF2AK2 P19525 1/20 0.39
CCNA2 P20248 1/20 0.39
CCND1 P24385 1/20 0.39
CCNE1 P24864 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12116420 0.90 ALK (0.40)
SCHEMBL31841 0.86 CHUK (0.39) CA1CA2CA4CA6CCNB2
SCHEMBL15803481 0.86 AR (0.41) AHRCA1CA2CA4CA6
SCHEMBL17996091 0.86 AHR (0.46) AHRCA1CA2CA4CA6
SCHEMBL29520180 0.85 AHR (0.52) AHRPGRKIF11ALDH1A1HSD17B10
SCHEMBL29438560 0.85 AHR (0.52) AHRPGRKIF11ALDH1A1HSD17B10
SCHEMBL31619 0.85 AHR (0.52) AHRPGRKIF11ALDH1A1HSD17B10
SCHEMBL21346765 0.84 KIF11 (0.57) AHRPGRKIF11CDK4CCND1
SCHEMBL23162509 0.83 AR (0.41) AHRCA1CA2CA4CA6
SCHEMBL1760310 0.82 AHR (0.45) AHRPGRKIF11ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278927-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-08 US disclosed
US-9278927-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-08 US disclosed
US-9224961-B2 Condensed-cyclic compound, organic light-emitting diode comprising the same and flat panel display device comprising the organic light-emitting diode SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-29 US disclosed
US-9224961-B2 Condensed-cyclic compound, organic light-emitting diode comprising the same and flat panel display device comprising the organic light-emitting diode SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-29 US disclosed
US-9090590-B2 Organic compounds for electroluminescent devices MERCK PATENT GMBH (DE) 2015-07-28 US disclosed
US-9090590-B2 Organic compounds for electroluminescent devices MERCK PATENT GMBH (DE) 2015-07-28 US disclosed
US-9090590-B2 Organic compounds for electroluminescent devices MERCK PATENT GMBH (DE) 2015-07-28 US disclosed
US-8889270-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-18 US disclosed
US-8889270-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-18 US disclosed
US-20130053558-A1 ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-02-28 US disclosed
US-20130032787-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-07 US disclosed
US-20130032787-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-07 US disclosed
US-20120267613-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2012-10-25 US disclosed
US-20120267613-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2012-10-25 US disclosed
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 US disclosed
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 US disclosed
WO-2012011756-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES INCLUDING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-01-26 WO disclosed
WO-2011136520-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-11-03 WO disclosed
WO-2011057701-A1 ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-05-19 WO disclosed
WO-2011057701-A1 ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130032787-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME PER2, CRY2, TELO2 AHR 11/4885CA1 4010/4885CA2 3596/4885
US-20130053558-A1 ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES PIEZO1, EMC1, EPCAM AHR 2771/4885CA1 2416/4885CA2 3698/4885
US-20120097932-A1 CONDENSED-CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME AND FLAT PANEL DISPLAY DEVICE COMPRISING THE ORGANIC LIGHT-EMITTING DIODE OCIAD1, OCIAD2, CFD AHR 3282/4885CA1 3075/4885CA2 3823/4885
US-20120267613-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CYP1A1, CRY2 AHR 18/4885CA1 3865/4885CA2 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.