Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 3/20 | 0.36 |
| ▸ | RORA | P35398 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350531 | 0.89 | KDM4E (0.38) | KDM4EALDH1A1HPGDNR5A1RORA | |
| SCHEMBL21331849 | 0.88 | KMT2A (0.39) | FFAR1KMT2ALMNATSHRSLC22A12 | |
| SCHEMBL21350304 | 0.85 | SLC22A12 (0.52) | KDM4EMAPTSLC22A12 | |
| SCHEMBL21350303 | 0.82 | CASP3 (0.42) | KDM4EALDH1A1HPGDFFAR1NPC1 | |
| SCHEMBL21350532 | 0.80 | ELANE (0.41) | FFAR1TSHRSLC22A12NAMPTTP53 | |
| SCHEMBL21350623 | 0.80 | SLC22A12 (0.43) | KDM4EALDH1A1HPGDFFAR1SMN1; SMN2 | |
| SCHEMBL21350903 | 0.80 | PPARA (0.39) | FFAR1SMN1; SMN2TSHRSLC22A12GRM2 | |
| SCHEMBL28408871 | 0.80 | POLB (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL21331858 | 0.78 | KMT2A (0.40) | KMT2ATSHRSLC22A12NOTUM | |
| SCHEMBL21350909 | 0.77 | CYP4F2 (0.50) | ALDH1A1FFAR1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |