SCHEMBL21352276

SCHEMBL21352276

O=C(CCSSCCC(=O)Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
MAPT P10636 2/20 0.51
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
CYP19A1 P11511 1/20 0.47
KMT2A Q03164 4/20 0.47
HSD17B10 Q99714 2/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
ELANE P08246 1/20 0.43
FFAR1 O14842 1/20 0.42
TSHR P16473 1/20 0.41
ALOX15 P16050 2/20 0.41
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21367567 0.96 ALDH1A1 (0.49) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL21367568 0.91 ALDH1A1 (0.62) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL21368544 0.90 ALDH1A1 (0.44) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL10568529 0.88 PRSS1 (0.49) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL11120105 0.87 CYP2C19 (0.53) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL11086910 0.86 PRSS1 (0.47) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL11615414 0.85 PRSS1 (0.59) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL43742 0.85 KMT2A (0.61) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL28512525 0.85 PRSS1 (0.46) ALDH1A1MAPTPRSS1PRSS2PRSS3
SCHEMBL14866210 0.85 KMT2A (0.48) ALDH1A1MAPTPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110272568-B Phenolic resin composition and use thereof in rubber compositions for reducing hysteresis SI集团有限公司 2023-05-12 CN disclosed
EP-3765310-A1 FUNCTIONALIZED ORGANOSULFUR COMPOUND FOR REDUCING HYSTERESIS IN A RUBBER ARTICLE SI Group, Inc. (US) 2021-01-20 EP disclosed
CN-112105509-A Functionalized organosulfur compounds for reducing hysteresis in rubber articles SI集团有限公司 2020-12-18 CN disclosed
US-10851224-B2 Phenolic resin composition and the use thereof in a rubber composition to reduce hysteresis SI GROUP, INC. (US) 2020-12-01 US disclosed
US-10851224-B2 Phenolic resin composition and the use thereof in a rubber composition to reduce hysteresis SI GROUP, INC. (US) 2020-12-01 US disclosed
US-20190284371-A1 FUNCTIONALIZED ORGANOSULFUR COMPOUND FOR REDUCING HYSTERESIS IN A RUBBER ARTICLE SI GROUP, INC. 2019-09-19 US disclosed
US-20190284371-A1 FUNCTIONALIZED ORGANOSULFUR COMPOUND FOR REDUCING HYSTERESIS IN A RUBBER ARTICLE SI GROUP, INC. 2019-09-19 US disclosed
WO-2019178373-A1 PHENOLIC RESIN COMPOSITION AND THE USE THEREOF IN A RUBBER COMPOSITION TO REDUCE HYSTERESIS SI GROUP, INC. (US) 2019-09-19 WO disclosed
WO-2019178381-A1 FUNCTIONALIZED ORGANOSULFUR COMPOUND FOR REDUCING HYSTERESIS IN A RUBBER ARTICLE SI GROUP, INC. (US) 2019-09-19 WO disclosed
WO-2019178381-A1 FUNCTIONALIZED ORGANOSULFUR COMPOUND FOR REDUCING HYSTERESIS IN A RUBBER ARTICLE SI GROUP, INC. (US) 2019-09-19 WO disclosed
WO-2019178373-A1 PHENOLIC RESIN COMPOSITION AND THE USE THEREOF IN A RUBBER COMPOSITION TO REDUCE HYSTERESIS SI GROUP, INC. (US) 2019-09-19 WO disclosed
US-20190284370-A1 PHENOLIC RESIN COMPOSITION AND THE USE THEREOF IN A RUBBER COMPOSITION TO REDUCE HYSTERESIS SI GROUP, INC. 2019-09-19 US disclosed
US-20190284370-A1 PHENOLIC RESIN COMPOSITION AND THE USE THEREOF IN A RUBBER COMPOSITION TO REDUCE HYSTERESIS SI GROUP, INC. 2019-09-19 US disclosed
EP-3539794-A1 PHENOLIC RESIN COMPOSITION AND THE USE THEREOF IN A RUBBER COMPOSITION TO REDUCE HYSTERESIS SI Group, Inc. (US) 2019-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10851224-B2 Phenolic resin composition and the use thereof in a rubber composition to reduce hysteresis POP1, TERT, SRM ALDH1A1 1771/4885MAPT 2872/4885PRSS1 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.