Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555213 | 0.79 | TP53 (0.42) | PKMMEN1KMT2ATP53IDO1 | |
| SCHEMBL21352405 | 0.79 | MEN1 (0.39) | PKMMEN1KMT2ATP53LMNA | |
| SCHEMBL1710859 | 0.77 | MEN1 (0.56) | PKMMEN1KMT2ATP53PKLR | |
| SCHEMBL21352389 | 0.77 | ENPP2 (0.46) | PKMMEN1KMT2AIDO1CYP1A2 | |
| SCHEMBL15331970 | 0.76 | POLB (0.43) | MEN1KMT2ATP53LMNATSHR | |
| SCHEMBL2556097 | 0.73 | LIPG (0.38) | PKMMEN1KMT2APKLRIDO1 | |
| Pyrrole SCHEMBL13725855 | 0.71 | MEN1 (0.50) | PKMMEN1KMT2ATP53PKLR | |
| SCHEMBL17485375 | 0.68 | LPL (0.47) | — | |
| SCHEMBL15332827 | 0.68 | KMT2A (0.42) | MEN1KMT2ATP53LMNASMN1; SMN2 | |
| SCHEMBL8502514 | 0.67 | IDO1 (0.40) | MEN1KMT2ATP53IDO1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |