SCHEMBL2135407

SCHEMBL2135407

O=[N+]([O-])c1ccc(-c2ccccc2P(=O)(O)S)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HTR7 P34969 1/20 0.46
POLB P06746 2/20 0.44
MAPK1 P28482 1/20 0.44
CA1 P00915 3/20 0.42
CA2 P00918 2/20 0.42
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
IKBKB O14920 1/20 0.41
SCN2A Q99250 1/20 0.41
CA12 O43570 2/20 0.40
MMP2 P08253 2/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28593785 0.87 POLB (0.46) MEN1KMT2AHTR7POLBMAPK1
SCHEMBL6962574 0.80 CA1 (0.48) MEN1KMT2AHTR7POLBMAPK1
SCHEMBL1256220 0.79 GPR84 (0.43) POLBCA2ALDH1A1
SCHEMBL23093961 0.77 PTPRC (0.42) MEN1KMT2APOLBCES1ALDH1A1
SCHEMBL28240316 0.75 ALDH1A1 (0.58) MEN1KMT2AHTR7POLBMAPK1
SCHEMBL9476747 0.75 KCNJ1 (0.38) MEN1KMT2APOLBMAPK1CA1
SCHEMBL11126615 0.75 MEN1 (0.39) MEN1KMT2APOLBCA1CA2
SCHEMBL1539358 0.73 IKBKB (0.56) MEN1KMT2AHTR7POLBMAPK1
SCHEMBL2818370 0.73 ALDH1A1 (0.50) MEN1KMT2AHTR7POLBMAPK1
SCHEMBL28574636 0.72 ALDH1A1 (0.52) MEN1KMT2APOLBCA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4365172-A1 HETEROCYCLIC COMPOUND AND HARMFUL-ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME Sumitomo Chemical Company, Limited (JP) 2024-05-08 EP disclosed
WO-2023167279-A1 METHOD FOR CONTROLLING HARMFUL ARTHROPODS OR HARMFUL NEMATODES USING ZOANTHAMINE ANALOG 住友化学株式会社 2023-09-07 WO disclosed
EP-4053107-A1 CRYSTAL OF 3-(DIFLUOROMETHYL)-1-METHYL-N-(1,1,3-TRIMETHYL-2,3-DIHYDRO-1H-INDEN-4-YL)-1H-PYRAZOLE-4-CARBOXAMIDE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2022-09-07 EP disclosed
EP-3949708-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-02-09 EP disclosed
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
US-20140196631-A1 VISUAL ASSAYS FOR COATINGS INCORPORATING BIOACTIVE ENZYMES FOR CATALYTIC FUNCTIONS REACTIVE SURFACE, LTD. (US) 2014-07-17 US disclosed
US-20140193889-A1 ENZYMATIC ANTIMICROBIAL AND ANTIFOULING COATINGS AND POLYMERIC MATERIALS REACTIVE SURFACES, LTD. (US) 2014-07-10 US disclosed
US-20120097194-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Catalytic Function REACTIVE SURFACES, LTD. (US) 2012-04-26 US disclosed
US-20110250626-A1 Visual Assays for Coatings Incorporating Bioactive Enzymes for Catalytic Functions REACTIVE SURFACES, LTD. (US) 2011-10-13 US disclosed
US-20110240064-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Cleaning a Surface REACTIVE SURFACES, LTD. (US) 2011-10-06 US disclosed
US-20100248334-A1 Biological active coating components, coatings, and coated surfaces REACTIVE SURFACES, LTD. 2010-09-30 US disclosed
US-20100210745-A1 Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes REACTIVE SURFACES, LTD. (US) 2010-08-19 US disclosed
US-20090238811-A1 Enzymatic Antimicrobial and Antifouling Coatings and Polymeric Materials REACTIVE SURFACES LTD. 2009-09-24 US disclosed