SCHEMBL1256220

SCHEMBL1256220

O=P(O)(S)c1ccccc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.43
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
BCAT2 O15382 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
ACP3 P15309 2/20 0.38
BACE1 P56817 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
PTPN5 P54829 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1965079 0.83 ALDH1A1 (0.44) GPR84ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL563975 0.83 POLB (0.47) GPR84ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL2135407 0.79 MEN1 (0.47) ALDH1A1CA2POLB
SCHEMBL28495219 0.79 BCAT2 (0.44) GPR84ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL11770352 0.79 GPR84 (0.43) GPR84ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL30729584 0.79 ACP3 (0.47) GPR84ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL11144673 0.78 ALDH1A1 (0.42) ALDH1A1HPGDBCL2L1HSD17B10HDAC4
SCHEMBL3646058 0.78 CA2 (0.46) GPR84ALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL29822328 0.78 CA2 (0.46) GPR84ALDH1A1HPGDBCL2L1HSD17B10
Phosphoric Acid SCHEMBL1281473 0.77 ALDH1A1 (0.52) GPR84ALDH1A1HPGDBCL2L1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732895-B1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2016-11-16 EP disclosed
CN-102548981-B N1-acyl-5-fluoropyrimidinone derivatives DOW AGROSCIENCES LLC 2015-05-13 CN disclosed
CN-101977900-B 5-fluoro pyrimidine derivatives DOW AGROSCIENCES LLC (US) 2013-11-27 CN disclosed
CN-102056915-A 2-alkynyl-6-pyridin-2-yl-pyridazinones, 2-alkynyl-6-pyridin-2-yl-dihydropyridazinones, 2-alkynyl-6-pyrimidin-2-yl-pyridazinones and 2-alkynyl-6-pyrimidin-2-yl-dihydropyridazinones and their use as fungicides DOW AGROSCIENCES LLC 2011-05-11 CN disclosed
US-7935826-B2 Insecticidal N-substituted (heteroaryl)cycloalkyl sulfoximines DOW AGROSCIENCES LLC (US) 2011-05-03 US disclosed
US-20110039904-A1 Alcohol alkoxylates, agents comprising the same and use of the alcohol alkoxylates as adjuvants in the agrochemical field BASF SE (DE) 2011-02-17 US disclosed
CN-101977900-A 5-fluoro pyrimidine derivatives DOW AGROSCIENCES LLC (US) 2011-02-16 CN disclosed
US-20100210461-A1 Compositions comprising alcohol alkoxylates, and use of the alcohol alkoxylates as adjuvant for the agrochemical sector BASF SE (DE) 2010-08-19 US disclosed
US-20100184603-A1 Alcohol alkoxylates, compositions containing these, and use of the alcohol alkoxylates as adjuvants for the agrochemical field BASF SE (DE) 2010-07-22 US disclosed
US-7678920-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-03-16 US disclosed
US-20100004290-A1 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)CYCLOALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-01-07 US disclosed
US-20050228027-A1 Insecticidal N-substituted sulfoximines CORTEVA AGRISCIENCE LLC 2005-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210461-A1 Compositions comprising alcohol alkoxylates, and use of the alcohol alkoxylates as adjuvant for the agrochemical sector ACOX3, PAOX, HAO2 GPR84 2398/4885ALDH1A1 983/4885HPGD 1160/4885
US-20110039904-A1 Alcohol alkoxylates, agents comprising the same and use of the alcohol alkoxylates as adjuvants in the agrochemical field CHRM1, CHRM2, AP2M1 GPR84 1934/4885ALDH1A1 389/4885HPGD 2060/4885
US-20100004290-A1 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)CYCLOALKYL SULFOXIMINES DDT, MSL1, STS GPR84 1010/4885ALDH1A1 3453/4885HPGD 3468/4885
US-20100184603-A1 Alcohol alkoxylates, compositions containing these, and use of the alcohol alkoxylates as adjuvants for the agrochemical field ACOX3, PAOX, ADH5 GPR84 3194/4885ALDH1A1 930/4885HPGD 1939/4885
US-20050228027-A1 Insecticidal N-substituted sulfoximines GSS, STS, SMS GPR84 1964/4885ALDH1A1 3325/4885HPGD 2521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.