SCHEMBL2135451

SCHEMBL2135451

O=C(O)/C(O)=C(O)/C(O)=C(O)/C(O)=C(O)/C(O)=C(O)/C(O)=C(\O)C(O)C(O)C(O)C(O)C(O)C(O)C(O)C(O)CO

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.55
LMNA P02545 2/20 0.52
TDP1 Q9NUW8 1/20 0.46
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887710 1.00 PDE4A (0.55) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL29563836 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL19952979 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL3067831 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL258100 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL19952978 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL288150 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL8769028 0.87 PDE4A (0.43) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL9698714 0.80 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL5670801 0.78 PDE4A (0.83) PDE4ALMNATDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6212186-A None JP disclosed
EP-2629790-B1 METHOD TO INCREASE THE GROWTH VELOCITY OF HUMAN INFANTS SWEDISH ORPHAN BIOVITRUM AB PUBL (SE) 2016-08-24 EP disclosed
US-20150297683-A1 METHOD TO INCREASE THE ABSORPTION OF UNSATURATED FATTY ACIDS BY HUMAN INFANTS SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2015-10-22 US disclosed
WO-2015144219-A1 METHOD OF TREATMENT SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2015-10-01 WO disclosed
US-20150191714-A1 FORMULATIONS OF RECOMBINANT HUMAN BILE SALT-STIMULATED LIPASE SWEDISH ORPHAN BIOVITRUM AB(PUBL) (SE) 2015-07-09 US disclosed
US-8986759-B2 Method to increase the growth velocity of human infants Swedish Orphan Biovitrum AB (pub) (SE) 2015-03-24 US disclosed
US-8986682-B2 Method to increase the absorption of unsaturated fatty acids by human infants SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2015-03-24 US disclosed
EP-2760467-A1 IMPROVED FORMULATIONS OF RECOMBINANT HUMAN BILE SALT-STIMULATED LIPASE Swedish Orphan Biovitrum AB (publ) (SE) 2014-08-06 EP disclosed
EP-2629789-A1 METHOD TO INCREASE THE ABSORPTION OF UNSATURATED FATTY ACIDS BY HUMAN INFANTS Swedish Orphan Biovitrum AB (Publ) (SE) 2013-08-28 EP disclosed
EP-2629790-A1 Method to increase the growth velocity of human infants Swedish Orphan Biovitrum AB (Publ) (SE) 2013-08-28 EP disclosed
CN-103200957-A Method to increase the growth velocity of human infants SWEDISH ORPHAN BIOVITRUM AB PUBL 2013-07-10 CN disclosed
CN-103189070-A Method to increase the absorption of unsaturated fatty acids by human infants SWEDISH ORPHAN BIOVITRUM AB PUBL 2013-07-03 CN disclosed
WO-2013048313-A1 IMPROVED FORMULATIONS OF RECOMBINANT HUMAN BILE SALT-STIMULATED LIPASE SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2013-04-04 WO disclosed
US-20120100126-A1 Method to Increase the Growth Velocity of Human Infants SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2012-04-26 US disclosed
US-20120100127-A1 Method to Increase the Absorption of Unsaturated Fatty Acids by Human Infants SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2012-04-26 US disclosed
WO-2012052060-A1 METHOD TO INCREASE THE GROWTH VELOCITY OF HUMAN INFANTS SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2012-04-26 WO disclosed
WO-2012052059-A1 METHOD TO INCREASE THE ABSORPTION OF UNSATURATED FATTY ACIDS BY HUMAN INFANTS SWEDISH ORPHAN BIOVITRUM AB (PUBL) (SE) 2012-04-26 WO disclosed
JP-H06212186-A PRODUCTION OF EICOSAPENTAENOIC ACID FROM RED ALGA FUDARAKU AGENCY OF IND SCIENCE & TECHNOL 1994-08-02 JP disclosed