Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135451 | 0.87 | PDE4A (0.55) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL887710 | 0.87 | PDE4A (0.55) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL288150 | 0.81 | PDE4A (0.59) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL19952979 | 0.81 | PDE4A (0.59) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL258100 | 0.81 | PDE4A (0.59) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL29563836 | 0.81 | PDE4A (0.59) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL19952978 | 0.81 | PDE4A (0.59) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL3067831 | 0.81 | PDE4A (0.59) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL3872092 | 0.70 | PDE4A (0.50) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9698714 | 0.70 | PDE4A (0.59) | PDE4ALMNATDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629602-B1 | 3,4-Dihydroxychalcone derivatives | NIPPON HYPOX LAB INC (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0629602-A1 | 3,4-Dihydroxychalcone derivatives | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5276058-A | Antiinflammatory agents | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1994-01-04 | — | — | US | disclosed |