SCHEMBL887710

SCHEMBL887710

O=C(O)/C(O)=C(O)/C(O)=C(O)/C(O)=C(O)/C(O)=C(O)/C(O)=C(O)/C(O)=C(\O)C(O)C(O)C(O)C(O)C(O)C(O)C(O)C(O)CO

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.55
LMNA P02545 2/20 0.52
TDP1 Q9NUW8 1/20 0.46
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2135451 1.00 PDE4A (0.55) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL29563836 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL19952979 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL3067831 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL258100 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL19952978 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL288150 0.92 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL8769028 0.87 PDE4A (0.43) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL9698714 0.80 PDE4A (0.59) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL5670801 0.78 PDE4A (0.83) PDE4ALMNATDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200046831-A1 NANOEMULSION COMPRISING IMIDAZOQUINOLINE-BASED MATERIAL AND USE THEREOF DANDI BIOSCIENCE INC. (KR) 2020-02-13 US claimed
US-9205108-B2 Treatment of traumatic brain injury by using gallium compounds to reduce oxidative stress levels TROUP JAN M (US) 2015-12-08 US claimed
US-20150306138-A1 TREATMENT OF TRAUMATIC BRAIN INJURY BY USING GALLIUM COMPOUNDS TO REDUCE OXIDATIVE STRESS LEVELS TROUP JAN M (US) 2015-10-29 US claimed
US-20130045287-A1 Treatment for Concussion using Gallium Compounds TROUP JAN M (US) 2013-02-21 US claimed
US-20200046831-A1 NANOEMULSION COMPRISING IMIDAZOQUINOLINE-BASED MATERIAL AND USE THEREOF DANDI BIOSCIENCE INC. (KR) 2020-02-13 US disclosed
US-20190255100-A1 TREATMENT OF CARDIOVASCULAR DISEASE BY USING GALLIUM COMPOUNDS TO BIND CALCIFIED LESIONS LIPIDRISK, LLC 2019-08-22 US disclosed
US-10259003-B2 Omega-3 spray THE PLANT BASED COMPANY (US) 2019-04-16 US disclosed
US-20180093287-A1 OMEGA-3 SPRAY THE PLANT BASED COMPANY 2018-04-05 US disclosed
EP-2341125-B1 ENHANCED PRODUCTION OF LIPIDS CONTAINING POLYENOIC FATTY ACIDS BY HIGH DENSITY CULTURES OF EUKARYOTIC MICROBES IN FERMENTORS DSM IP ASSETS BV (NL) 2017-09-27 EP disclosed
EP-2338974-B1 Enhanced production of lipids containing polyenoic fatty acids by high density cultures of microorganisms of the order Thraustochytriales in fermentors DSM IP ASSETS BV (NL) 2017-09-27 EP disclosed
US-20160106137-A1 PROTEIN BEVERAGE AND METHOD OF MAKING THE SAME NEXT PROTEINS INC (US) 2016-04-21 US disclosed
US-9220292-B2 Protein beverage and method of making same NEXT PROBLEMS, INC. (US) 2015-12-29 US disclosed
US-20070148305-A1 PROTEIN BEVERAGE AND METHOD OF MAKING THE SAME DAVINAS, LLC 2007-06-28 US disclosed
US-7205018-B2 Carbonated protein drink and method of making NEXT PROTEINS, INC. (US) 2007-04-17 US disclosed
WO-2007027213-A1 HIGH ENERGY CARBONATED PROTEIN DRINK AND METHOD OF MAKING NEXT PROTEINS, INC. (US) 2007-03-08 WO disclosed
US-20060148757-A1 Method of inhibiting formation of volatile aldehydes and/or decomposition of fatty acids and use thereof Hayashibara Co., Ltd. (JP) 2006-07-06 US disclosed
US-20060147602-A1 High energy carbonated protein drink and method of making NEXT PROTEINS, INC. 2006-07-06 US disclosed
US-20060083844-A1 Carbonated protein drink and method of making DAVINAS, LLC 2006-04-20 US disclosed
WO-2006042222-A2 CARBONATED PROTEIN DRINK AND METHOD OF MAKING NEXT PROTEINS, INC. (US) 2006-04-20 WO disclosed
EP-1600496-A1 METHOD OF INHIBITING FORMATION OF VOLATILE ALDEHYDES AND/OR DECOMPOSITION OF FATTY ACIDS AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2005-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045287-A1 Treatment for Concussion using Gallium Compounds GRIK5, FABP7, GRM5 PDE4A 1882/4885LMNA 4012/4885TDP1 2617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.