SCHEMBL213570

SCHEMBL213570

CC(O)c1ccc(N)cc1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 4/20 0.44
ALDH1A1 P00352 5/20 0.37
GAA P10253 4/20 0.37
TSHR P16473 3/20 0.37
PDE10A Q9Y233 1/20 0.37
PDE2A O00408 1/20 0.36
ALOX5 P09917 1/20 0.34
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
USP2 O75604 2/20 0.33
POLB P06746 2/20 0.33
KMT2A Q03164 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 2/20 0.33
THRB P10828 2/20 0.33
RECQL P46063 2/20 0.33
PKM P14618 1/20 0.33
APEX1 P27695 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17385275 1.00 CASP1 (0.44) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL446559 0.82 ALDH1A1 (0.41) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL29940754 0.82 ALDH1A1 (0.41) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL29368425 0.81 CASP1 (0.48) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL49477 0.81 CASP1 (0.48) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL18677675 0.81 CASP1 (0.42) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL5486247 0.81 CASP1 (0.48) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL6152512 0.80 CASP1 (0.50) CASP1ALDH1A1GAATSHRPDE10A
SCHEMBL9770071 0.80 ALDH1A1 (0.50) CASP1ALDH1A1GAATSHRPDE10A
Hydrochloric Acid SCHEMBL11217552 0.79 CASP1 (0.46) CASP1ALDH1A1GAATSHRPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3096735-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME Combe International Ltd. (US) 2016-11-30 EP claimed
CN-105916482-A Gradual hair color compositions and methods of use thereof 酷姆国际公司 2016-08-31 CN claimed
EP-1674075-B1 Hair colouring process comprising a cleaning step ORÉAL L (FR) 2016-07-20 EP claimed
WO-2015112789-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME COMBE INTERNATIONAL LTD. (US) 2015-07-30 WO claimed
EP-1674075-A1 Colored hair treating process with a composition comprising a specific non ionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
EP-1674074-A1 Colored hair treating process with a composition comprising a specific non ionic and/or an amphoteric and/or a mild anionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
US-7066968-B2 Efficient two-step method of coloring and lightening hair with less damage UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2006-06-27 US claimed
US-7041142-B2 Two step hair coloring compositions delivering deeper, long-lasting color UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2006-05-09 US claimed
US-20060075580-A1 TWO STEP HAIR COLORING COMPOSITIONS DELIVERING DEEPER, LONG-LASTING COLOR UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-04-13 US claimed
US-20050193501-A1 Efficient two-step method of coloring and lightening hair with less damage UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-09-08 US claimed
WO-1993007849-A1 HAIR-DYEING AGENT CONTAINING AMINOPYRAZOLE DERIVATIVES, AND NEW PYRAZOLE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1993-04-29 WO claimed
EP-0252351-B1 5-ALKOXY-2,4-DIAMINO-ALKYLBENZENES AND HAIR DYES CONTAINING SAME Wella Aktiengesellschaft (DE) 1990-09-12 EP claimed
EP-0375977-A1 Oxidation hairdyeing composition based upon diaminopyrazole derivatives, and these diaminopyrazole derivatives Wella Aktiengesellschaft (DE) 1990-07-04 EP claimed
US-4904275-A OXIDIZER L'OREAL (FR) 1990-02-27 US claimed
US-4854935-A OXIDATION COLOR DYE COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
US-4797130-A DYE DEVELOPERS GOOD FOR RED COLORING WELLA AKTIENGESELLSCHAFT (DE) 1989-01-10 US claimed
EP-0252351-A1 5-Alkoxy-2,4-diamino-alkylbenzenes and hair dyes containing same Wella Aktiengesellschaft (DE) 1988-01-13 EP claimed
US-4713080-A OXIDATIVE COLORING WELLA AKTIENGESELLSCHAFT (DE) 1987-12-15 US claimed
US-4661114-A COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1987-04-28 US claimed
US-4473375-A COUPLER AND DEVELOPER FOR OXIDATION COLOR DYES WELLA AKTIENGESELLSCHAFT (DE) 1984-09-25 US claimed