SCHEMBL446559

SCHEMBL446559

CC(O)c1cc(N)ccc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
GAA P10253 4/20 0.41
CASP1 P29466 3/20 0.39
MAPT P10636 3/20 0.38
THRB P10828 2/20 0.38
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
APEX1 P27695 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
MCL1 Q07820 1/20 0.38
KDM4E B2RXH2 1/20 0.37
TSHR P16473 4/20 0.37
PDE10A Q9Y233 1/20 0.37
CYP3A4 P08684 4/20 0.36
ALOX15 P16050 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29940754 1.00 ALDH1A1 (0.41) ALDH1A1GAACASP1MAPTTHRB
Sulfuric Acid SCHEMBL2987321 0.90 ALDH1A1 (0.52) ALDH1A1GAACASP1MAPTTHRB
SCHEMBL11584910 0.84 CASP1 (0.38) ALDH1A1GAACASP1MAPTTHRB
SCHEMBL5555398 0.83 GAA (0.35) ALDH1A1GAAMAPTKDM4ETSHR
SCHEMBL2770647 0.82 ALDH1A1 (0.44) ALDH1A1GAAMAPTTDP1MEN1
SCHEMBL17385275 0.82 CASP1 (0.44) ALDH1A1GAACASP1MAPTTHRB
SCHEMBL213570 0.82 CASP1 (0.44) ALDH1A1GAACASP1MAPTTHRB
SCHEMBL33893 0.81 CASP1 (0.42) ALDH1A1GAACASP1MAPTTHRB
SCHEMBL29433029 0.81 CASP1 (0.42) ALDH1A1GAACASP1MAPTTHRB
SCHEMBL28252731 0.81 CASP1 (0.42) ALDH1A1GAACASP1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1952 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
EP-4731170-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE Wella Germany GmbH (DE) 2026-04-29 EP claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
EP-4552630-A1 RESORCINOL FREE PERMANENT HAIR COLOR COMPOSITION AND METHOD Wella Operations US, LLC (US) 2025-05-14 EP claimed
CN-115980205-B Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product 江苏省食品药品监督检验研究院 2025-04-22 CN claimed
WO-2025031867-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE WELLA GERMANY GMBH (DE) 2025-02-13 WO claimed
WO-2025008339-A1 OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2025-01-09 WO claimed
US-20240342067-A1 Hair Coloring Compositions Comprising 2-Amino-1-Propanol As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-17 US claimed
US-4985042-A New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1991-01-15 US claimed
EP-0252351-B1 5-ALKOXY-2,4-DIAMINO-ALKYLBENZENES AND HAIR DYES CONTAINING SAME Wella Aktiengesellschaft (DE) 1990-09-12 EP claimed
US-4954131-A Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1990-09-04 US claimed
US-4904275-A OXIDIZER L'OREAL (FR) 1990-02-27 US claimed
US-4863480-A OXIDATION COLOR DYES THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) 1989-09-05 US claimed
US-4854935-A OXIDATION COLOR DYE COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
US-4840639-A OXIDATIVE DYEING; MIXTURE WITH COUPLER AND DEVELOPER WELLA AKTIENGESELLSCHAFT (DE) 1989-06-20 US claimed
EP-0252351-A1 5-Alkoxy-2,4-diamino-alkylbenzenes and hair dyes containing same Wella Aktiengesellschaft (DE) 1988-01-13 EP claimed
US-4588410-A DEVELOPERS, COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1986-05-13 US claimed
US-4324553-A OXIDATION COLOR DYES L'OREAL (FR) 1982-04-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents PHOSPHO1, ALDH7A1, AASDHPPT ALDH1A1 173/4885GAA 4556/4885CASP1 2214/4885
US-12636241-B1 Method and composition for oxidative hair coloring POLB, DAO, ALPP ALDH1A1 200/4885GAA 4124/4885CASP1 4235/4885
US-20240342067-A1 Hair Coloring Compositions Comprising 2-Amino-1-Propanol As Alkalising Agents ALDH7A1, PTMA, AAAS ALDH1A1 26/4885GAA 3051/4885CASP1 2608/4885
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) DEGS1, SGMS1, FABP4 ALDH1A1 3076/4885GAA 2009/4885CASP1 4407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.