Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.40 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CDA | P32320 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PYGM | P11217 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751008 | 0.83 | LMNA (0.42) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA | |
| SCHEMBL10903331 | 0.83 | LMNA (0.42) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA | |
| SCHEMBL9213688 | 0.81 | SLC29A1 (0.44) | SLC29A1SLC28A1SLC28A2SLC28A3MEN1 | |
| SCHEMBL28159962 | 0.80 | LMNA (0.40) | SLC29A1SLC28A1SLC28A2SLC28A3MEN1 | |
| SCHEMBL6906558 | 0.80 | LMNA (0.45) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA | |
| SCHEMBL3630509 | 0.80 | LMNA (0.45) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA | |
| SCHEMBL27284021 | 0.80 | SLC28A1 (0.39) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA | |
| SCHEMBL25188377 | 0.79 | CDA (0.43) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA | |
| SCHEMBL10903345 | 0.78 | CDA (0.42) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA | |
| SCHEMBL31436719 | 0.78 | CDA (0.42) | SLC29A1SLC28A1SLC28A2SLC28A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198958-A1 | NUCLEIC ACID POLYMERS | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |
| EP-3765476-A2 | MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES | Janssen Pharmaceutica NV (BE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019175260-A2 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE IN TAUOPATHIES | JANSSEN PHARMACEUTICA NV (BE) | 2019-09-19 | — | — | WO | disclosed |