SCHEMBL4751008

SCHEMBL4751008

CCC1(N)C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ CDA P32320 5/20 0.41
▸ SLC28A1 O00337 1/20 0.41
▸ SLC28A2 O43868 1/20 0.41
▸ SLC29A1 Q99808 1/20 0.41
▸ SLC28A3 Q9HAS3 1/20 0.41
▸ MTOR P42345 2/20 0.39
▸ THRB P10828 1/20 0.39
▸ MDM2 Q00987 1/20 0.39
▸ NCOA1 Q15788 1/20 0.39
▸ NCOA3 Q9Y6Q9 1/20 0.39
▸ GMNN O75496 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ DNMT1 P26358 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10903331 0.88 LMNA (0.42) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL10903345 0.85 CDA (0.42) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL28159962 0.85 LMNA (0.40) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL6906558 0.85 LMNA (0.45) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL3630509 0.85 LMNA (0.45) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL25188377 0.84 CDA (0.43) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL29845228 0.83 CDA (0.41) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL21357413 0.83 SLC29A1 (0.40) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL31436719 0.82 CDA (0.42) LMNASMN1; SMN2ALDH1A1POLBCDA
SCHEMBL21357702 0.82 CDA (0.40) LMNASMN1; SMN2ALDH1A1POLBCDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008137466-A2 NUCLEIC ACID QUANTITATION METHODS ASURAGEN, INC. (US) 2008-11-13 — — WO disclosed
US-20080274458-A1 NUCLEIC ACID QUANTITATION METHODS ASURAGEN, INC. 2008-11-06 — — US disclosed
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