Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438169 | 0.81 | MAPT (0.50) | L3MBTL1MAPTHPGD | |
| SCHEMBL14893567 | 0.80 | KCNK3 (0.49) | L3MBTL1MLYCD | |
| SCHEMBL4442981 | 0.80 | L3MBTL1 (0.61) | L3MBTL1MAPTCYP1A2CYP2C19POLB | |
| SCHEMBL1648325 | 0.79 | KDM4E (0.49) | L3MBTL1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL1902043 | 0.79 | ELANE (0.46) | L3MBTL1MAPTCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL307126 | 0.77 | CTSD (0.51) | L3MBTL1NPC1RAB9AHPGDHTT | |
| SCHEMBL21358396 | 0.76 | MLYCD (0.42) | MLYCDRAB9AHTT | |
| SCHEMBL3653595 | 0.76 | CTNNB1 (0.53) | L3MBTL1MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL21358357 | 0.75 | MLYCD (0.56) | MAPTMEN1KMT2AMLYCDKDM4E | |
| SCHEMBL14065615 | 0.75 | ABCB1 (0.45) | L3MBTL1MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765020-A1 | SPIROCYCLIC ROR-GAMMA MODULATORS | Escalier Biosciences B.V. (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019177997-A1 | SPIROCYCLIC ROR-GAMMA MODULATORS | ESCALIER BIOSCIENCES B.V. (US) | 2019-09-19 | — | — | WO | disclosed |