Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21359548 | 0.78 | ALK (0.56) | ACLYROCK2MCL1MELKROCK1 | |
| SCHEMBL22861261 | 0.75 | AKT1 (0.56) | ACLYROCK2MCL1MELKROCK1 | |
| SCHEMBL2905661 | 0.71 | MMP2 (0.68) | MCL1PTK2B | |
| SCHEMBL21359390 | 0.71 | MIF (0.51) | ACLYROCK2MELKROCK1 | |
| SCHEMBL19029524 | 0.71 | GRIK1 (0.56) | ACLYROCK2ROCK1 | |
| SCHEMBL21857726 | 0.71 | KMT2A (0.66) | ACLYROCK2MCL1MELKROCK1 | |
| SCHEMBL21359417 | 0.71 | MCL1 (0.47) | ACLYROCK2MCL1ROCK1 | |
| SCHEMBL21359504 | 0.70 | ACMSD (0.54) | ACLYROCK2ROCK1 | |
| SCHEMBL22861322 | 0.70 | MAPT (0.55) | ROCK2MCL1MELKROCK1ALK | |
| SCHEMBL14150115 | 0.69 | MMP2 (0.65) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178480-A1 | PYRAZOLE-CONTAINING MACROPHAGE MIGRATION INHIBITORY FACTOR INHIBITORS | YALE UNIVERSITY (US) | 2019-09-19 | — | — | WO | disclosed |