Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982533 | 0.94 | FAAH (0.39) | FAAHMGLLSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL8632296 | 0.92 | MGLL (0.41) | FAAHMGLLSMN1; SMN2MAPTFDPS | |
| SCHEMBL8829436 | 0.92 | MGLL (0.41) | FAAHMGLLSMN1; SMN2MAPTFDPS | |
| SCHEMBL8626067 | 0.92 | MGLL (0.41) | FAAHMGLLSMN1; SMN2MAPTFDPS | |
| SCHEMBL8629338 | 0.92 | MGLL (0.41) | FAAHMGLLSMN1; SMN2MAPTFDPS | |
| SCHEMBL8829443 | 0.86 | CHRM2 (0.34) | FAAHMGLLCHRM2CHRM4CHRM5 | |
| SCHEMBL3625111 | 0.84 | MGLL (0.41) | FAAHMGLLSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21033765 | 0.81 | FAAH (0.35) | FAAHMGLLSMN1; SMN2TSHRCHRM2 | |
| SCHEMBL9818026 | 0.79 | FAAH (0.37) | FAAHMGLLSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8893476 | 0.76 | FAAH (0.33) | FAAHMGLLSMN1; SMN2TSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533640-A | Targeting of tumor-associated macrophages of type M2 using melittin-based apoptosis-inducing peptides | 双亥生命科学株式会社 | 2021-03-19 | — | — | CN | disclosed |
| EP-3743024-A1 | OPHTHALMOLOGICAL SURGICAL SET AND A CONTACT LENS | Geuder AG (DE) | 2020-12-02 | — | — | EP | disclosed |
| WO-2019174683-A1 | OPHTHALMOLOGICAL SURGICAL SET AND A CONTACT LENS | GEUDER AG (DE) | 2019-09-19 | — | — | WO | disclosed |