Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829436 | 1.00 | MGLL (0.41) | MGLLFAAHGPR84FDPSFFAR1 | |
| SCHEMBL8626067 | 1.00 | MGLL (0.41) | MGLLFAAHGPR84FDPSFFAR1 | |
| SCHEMBL8632296 | 1.00 | MGLL (0.41) | MGLLFAAHGPR84FDPSFFAR1 | |
| SCHEMBL1982533 | 0.98 | FAAH (0.39) | MGLLFAAHGPR84FDPSFFAR1 | |
| SCHEMBL21360131 | 0.92 | FAAH (0.36) | MGLLFAAHFDPSALOX5KMT2A | |
| SCHEMBL3625111 | 0.88 | MGLL (0.41) | MGLLFAAHKMT2ASMN1; SMN2PTGER4 | |
| SCHEMBL23901063 | 0.84 | MGLL (0.41) | MGLLFAAHGPR84FDPSFFAR1 | |
| SCHEMBL21648859 | 0.84 | MGLL (0.41) | MGLLFAAHGPR84FDPSFFAR1 | |
| SCHEMBL21575529 | 0.84 | MGLL (0.41) | MGLLFAAHGPR84FDPSFFAR1 | |
| SCHEMBL23901147 | 0.84 | MGLL (0.41) | MGLLFAAHGPR84FDPSFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773439-A | Shiga toxin A subunit effector polypeptides, shiga toxin effector scaffolds and cell targeting molecules for site-specific conjugation | 分子模板公司 | 2022-07-22 | — | — | CN | disclosed |
| US-5849863-A | Cytolytic bradykinin antagonists | UNIVERSITY OF COLORADO (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0848718-A1 | CYTOLYTIC BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997009347-A1 | CYTOLYTIC BRADYKININ ANTAGONISTS | CORTECH, INC. (US) | 1997-03-13 | — | — | WO | disclosed |