SCHEMBL21360149

SCHEMBL21360149

Cc1cc(Br)ccc1O.Oc1ccccc1I

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTA1 P08263 3/20 0.42
ALOX15 P16050 2/20 0.41
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ESR1 P03372 5/20 0.40
ESR2 Q92731 4/20 0.40
PDE10A Q9Y233 1/20 0.38
HSD17B1 P14061 2/20 0.37
HSD17B2 P37059 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
HSP90AA1 P07900 1/20 0.37
KMT2A Q03164 1/20 0.37
DHODH Q02127 1/20 0.36
CES2 O00748 1/20 0.36
GALR3 O60755 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49677 0.82
Orthocresol SCHEMBL2034945 0.78 TRPA1 (0.46) ALOX15TP53TDP1ESR1ESR2
Orthocresol SCHEMBL21750821 0.77 TRPA1 (0.44) ALOX15TP53TDP1ESR1ESR2
O-Xylene SCHEMBL5492417 0.76 TSHR (0.50) ALOX15TP53TDP1NPC1RAB9A
SCHEMBL7674042 0.75 ALOX15 (0.48) ALOX15TP53TDP1ESR1ESR2
SCHEMBL40539 0.74
Propene SCHEMBL4958342 0.73 ALOX15 (0.46) ALOX15TP53TDP1ESR1ESR2
SCHEMBL5720 0.73
Hydrogen Sulfide SCHEMBL28872365 0.71
Hydrochloric Acid SCHEMBL28141447 0.71 ALDH1A1 (0.53) ALOX15TP53TDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019176859-A1 EPOXY RESIN COMPOSITION AND ELECTRONIC COMPONENT DEVICE 日立化成株式会社 2019-09-19 WO disclosed