Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.46 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749933 | 0.92 | CYP2D6 (0.44) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| Chlorothen SCHEMBL29707 | 0.85 | CYP2D6 (0.64) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| Chlorothen SCHEMBL29521748 | 0.84 | KDM4E (0.65) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL18912921 | 0.83 | CYP2D6 (0.43) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL7297232 | 0.78 | CYP2D6 (0.73) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL9866638 | 0.76 | CYP2D6 (0.72) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL7095181 | 0.75 | CHRM2 (0.69) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL10749349 | 0.74 | SSTR4 (0.35) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| Chlorothen SCHEMBL1649730 | 0.73 | LMNA (0.71) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 | |
| SCHEMBL10674626 | 0.70 | CYP2D6 (0.70) | CYP2D6CHRM2ADRA2ADRD1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10413487-B2 | Nail gel polish and its manufacturing method | Shanghai O'Nine Technologies Ltd. (CN) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10413487-B2 | Nail gel polish and its manufacturing method | POLR1C, NACA, PRKDC | CYP2D6 2473/4885CHRM2 4061/4885ADRA2A 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.