SCHEMBL21361135

SCHEMBL21361135

CN(C)P(=O)(O)OC[C@@H]1CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.53
RIN1 Q13671 1/20 0.53
P2RY6 Q15077 12/20 0.47
P2RY14 Q15391 2/20 0.47
NT5E P21589 2/20 0.47
POLB P06746 1/20 0.47
P2RY12 Q9H244 1/20 0.34
P2RY2 P41231 6/20 0.34
P2RY4 P51582 5/20 0.34
ROCK2 O75116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30177207 0.92 ABL1 (0.52) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL15144425 0.92 ABL1 (0.52) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL17589388 0.92 ABL1 (0.52) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL27158019 0.88 ABL1 (0.47) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL17589393 0.88 ABL1 (0.48) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL27159489 0.88 ABL1 (0.48) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL23607152 0.87 ABL1 (0.56) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL30892888 0.86 POLB (0.47) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL27158214 0.86 ABL1 (0.59) ABL1RIN1P2RY6P2RY14NT5E
SCHEMBL29975237 0.85 P2RY6 (0.49) ABL1RIN1P2RY6P2RY14NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10415036-B2 Morpholino oligonucleotide manufacturing method AJINOMOTO CO., INC. (JP) 2019-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10415036-B2 Morpholino oligonucleotide manufacturing method RNGTT, RNMT, NSUN2 ABL1 3019/4885RIN1 4695/4885P2RY6 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.