SCHEMBL29975237

SCHEMBL29975237

CCN(CC)CC.CCN(CC)CC.CN(C)P(=O)(OC[C@@H]1CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O1)N1C[C@@H](CP(=O)(O)O)O[C@@H](n2ccc(NC(=O)c3ccccc3)nc2=O)C1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 16/20 0.49
P2RY14 Q15391 2/20 0.49
ABL1 P00519 1/20 0.44
RIN1 Q13671 1/20 0.44
NT5E P21589 1/20 0.42
POLB P06746 1/20 0.40
P2RY2 P41231 3/20 0.35
P2RY4 P51582 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27158019 0.97 ABL1 (0.47) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL30733834 0.92 P2RY6 (0.42) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL27159489 0.90 ABL1 (0.48) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL29975337 0.90 ABL1 (0.53) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL29975095 0.89 ABL1 (0.39) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL30892888 0.87 POLB (0.47) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL21361135 0.85 ABL1 (0.53) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL27158214 0.85 ABL1 (0.59) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL27159640 0.85 ABL1 (0.42) P2RY6P2RY14ABL1RIN1NT5E
SCHEMBL27159494 0.85 ABL1 (0.42) P2RY6P2RY14ABL1RIN1NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US claimed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP claimed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO claimed
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2024-08-01 US disclosed
EP-4332111-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND Nippon Shinyaku Co., Ltd. (JP) 2024-03-06 EP disclosed
WO-2022230954-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2022-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254158-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, CYC1, MRM1 P2RY6 3552/4885P2RY14 4328/4885ABL1 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.