Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974139 | 0.91 | TDP1 (0.36) | TDP1CNR1FOLH1CAPN1CNR2 | |
| SCHEMBL21390226 | 0.79 | TDP1 (0.44) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL11983829 | 0.78 | TDP1 (0.42) | TDP1CNR1FOLH1CAPN1CNR2 | |
| SCHEMBL11983709 | 0.77 | CNR1 (0.43) | TDP1CNR1FOLH1CAPN1CNR2 | |
| SCHEMBL21206321 | 0.77 | PRSS1 (0.47) | TDP1CNR1MEN1ABL1LMNA | |
| SCHEMBL21361153 | 0.77 | TDP1 (0.62) | TDP1CNR1MEN1ABL1LMNA | |
| SCHEMBL22473613 | 0.76 | FAAH (0.42) | TDP1CNR1MEN1ABL1LMNA | |
| SCHEMBL11974137 | 0.76 | TDP1 (0.35) | TDP1CNR1FOLH1PRSS1PRSS2 | |
| SCHEMBL19034456 | 0.75 | TDP1 (0.45) | TDP1CNR1MEN1ABL1LMNA | |
| SCHEMBL20342144 | 0.75 | TDP1 (0.45) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10413621-B2 | Composition and methods for imaging cells | CASE WESTERN RESERVE UNIVERSITY (US) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10413621-B2 | Composition and methods for imaging cells | MCL1, TP53, HNRNPAB | TDP1 3017/4885CNR1 2138/4885MEN1 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.