Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361616 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MEN1GFERKMT2AHTR7 | |
| SCHEMBL23102285 | 0.87 | AKR1C3 (0.41) | ALDH1A1AKR1C3SMN1; SMN2CYP19A1HRH3 | |
| SCHEMBL21361542 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A1MEN1GFERKMT2AHTR7 | |
| SCHEMBL21361539 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2CYP19A1POLB | |
| SCHEMBL23102067 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GFERKMT2AHTR7HTR2A | |
| SCHEMBL21361466 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHTR7HTR2A | |
| SCHEMBL21361409 | 0.80 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2GAAHTR1A | |
| SCHEMBL21361487 | 0.80 | LMNA (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2CYP19A1 | |
| SCHEMBL21361537 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2CYP19A1POLBGAA | |
| SCHEMBL23102277 | 0.79 | NPSR1 (0.39) | ALDH1A1MEN1KMT2AAKR1C3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |