Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23102067 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTMAPTRECQL | |
| SCHEMBL23102064 | 0.87 | TGM2 (0.47) | ALDH1A1LMNATGM2 | |
| SCHEMBL23102085 | 0.81 | HTR6 (0.37) | ALDH1A1LMNAHTR2ATGM2DRD2 | |
| SCHEMBL23102269 | 0.81 | HTR1A (0.40) | ALDH1A1LMNAHTTMAPTRECQL | |
| SCHEMBL23102280 | 0.81 | HTR6 (0.36) | ALDH1A1LMNATGM2 | |
| SCHEMBL21361519 | 0.80 | ALDH1A1 (0.34) | ALDH1A1HTR2AHTR2CHTR7GAA | |
| SCHEMBL21361616 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTMAPTTSHR | |
| SCHEMBL21361542 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1LMNATSHRHTR7GAA | |
| SCHEMBL21361498 | 0.79 | LMNA (0.43) | ALDH1A1LMNAHTTMAPTTSHR | |
| SCHEMBL21361567 | 0.79 | NPSR1 (0.44) | ALDH1A1LMNATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |