Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099464 | 0.83 | KDM4E (0.66) | KDM4EALDH1A1CHRNA7GFERL3MBTL1 | |
| SCHEMBL23340098 | 0.80 | ADRA2A (0.54) | KDM4EALDH1A1CHRNA7GFERL3MBTL1 | |
| SCHEMBL4252814 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1CHRNA7GFERL3MBTL1 | |
| SCHEMBL10671655 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1CHRNA7GFERL3MBTL1 | |
| SCHEMBL23759665 | 0.79 | CHRNB2 (0.51) | CHRNA7CHRNB2CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL11446878 | 0.78 | CHRM2 (0.49) | KDM4EALDH1A1CHRNA7GFERL3MBTL1 | |
| SCHEMBL7420676 | 0.78 | CYP2D6 (0.77) | KDM4EALDH1A1CHRNA7GFERL3MBTL1 | |
| SCHEMBL164538 | 0.78 | LMNA (0.67) | ALDH1A1CHRNA7L3MBTL1MAPTSIGMAR1 | |
| SCHEMBL576454 | 0.78 | LMNA (0.67) | ALDH1A1CHRNA7L3MBTL1MAPTSIGMAR1 | |
| SCHEMBL576814 | 0.78 | LMNA (0.67) | ALDH1A1CHRNA7L3MBTL1MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |