Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664668 | 0.80 | MCL1 (0.65) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL941112 | 0.80 | MCL1 (0.65) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL25904738 | 0.75 | LMNA (0.82) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL20937648 | 0.74 | MCL1 (0.58) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL20853270 | 0.74 | CD274 (0.41) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL29939764 | 0.72 | RXFP1 (0.71) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL584871 | 0.72 | RXFP1 (0.71) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL9495716 | 0.72 | ALDH1A1 (0.64) | LMNAMAPK1PRNPRXFP1ALDH1A1 | |
| Dibenzothiophene SCHEMBL28857076 | 0.71 | GPR3 (0.58) | MCL1LMNAMAPK1PRNPRXFP1 | |
| SCHEMBL15697532 | 0.71 | PTPN2 (0.56) | MCL1LMNAMAPK1PRNPRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268361-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |