Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362282 | 0.92 | ALDH1A1 (0.44) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL12332481 | 0.89 | ALDH1A1 (0.43) | ALDH1A1LMNAALBMAPK1P2RY1 | |
| SCHEMBL21362298 | 0.83 | ALDH1A1 (0.64) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL31685317 | 0.82 | POLB (0.55) | P2RY1TAS1R3TAS1R1 | |
| SCHEMBL20324734 | 0.82 | P2RY1 (0.47) | ALDH1A1LMNAALBMAPK1P2RY1 | |
| SCHEMBL20224848 | 0.82 | STING1 (0.35) | ALDH1A1LMNAALBMAPK1P2RY1 | |
| SCHEMBL21133241 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21132979 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL20327576 | 0.81 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21417219 | 0.81 | ALDH1A1 (0.71) | ALDH1A1LMNAALBMAPK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |