Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23641893 | 0.86 | ALDH1A1 (0.61) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL12884872 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL21362217 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL21362282 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL4409629 | 0.79 | CYP1A2 (0.66) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL31685345 | 0.79 | HIF1A (0.62) | LMNAHIF1A | |
| Didanosine SCHEMBL16695883 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL5021456 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL1674335 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL16695885 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |